secara tradisional daun mangga arum

secara tradisional daun mangga arumanis digunakan oleh masyarakat untuk mengobati berbagai penyakit salah satunya adalah sebagai antidiabetes.penelitian ini bertujuan untuk mengetahui aktivitas dari ekstrak daun mangga arumanis serta mengatahui dosis yang paling efektif sebagai antidiabetes pada mencit. penelitian ini dilakukan dengan menggunakan metode tes toleransi glukosa oral yang diinduksi glukosa dengan dosis 3,9 g/kg bb mencit mencit dibagi menjadi 6 kelompok yaitu kontrol negatif,kontrol positif, pembanding glibenklamid dengan dosis 1,3 mg/kg bb mencit dan ekstrak uji daun mangga dengan dosis berturut-turut 2,1 mg/20 g bb mencit, 4,2 mg/20 g bbmencit, dan 8,4 mg/20 g bb mencit. parameter yang diamati adalah penurunan kadar glukosa darah. hasil yang di dapat menunjukan bahwa ekstrak daun mangga dengan dosisi 8,4 mg/20 g bbmencit mampu m,enurunkan kadar glukosa darah lebih besar dibandingkan dengan dosisi uji yang lain pada menit ke 180. uji statistik menggunakan ANOVA dengan selang kepercayaan 95% (alfa = 0,05) menunjukan adanya perbedaan bermakna penurunan kadar glukosa darah pada dosisi tersebut dibandingkan dengan kontrol positif. ekstrak daun mangga dengan dosis 8,4 mg/20 g bb mencit dibandingkan dengan pembanding glibenklamid menunjukan tidak adanya perbedaan bermakna. hasil penelitian ini mengidikasikan bahwa ekstrak daun mangga arumanis berpotensi sebagai anti diabete.
kata kunci : daun mangga arumanis, antidiabetes,glibenklamid, tes toleransi glukosa oral

Results (English) 1:

traditionally the mango leaves arumanis used by people to treat various diseases, one of which is as anti diabetic. this research aims to know the activities of extracts from leaves of mango arumanis and do know the most effective dose as the anti diabetic on mice. the research was conducted using the oral glucose tolerance test method that induced glucose with a dose of 3.9 g/kg murine murine divided into 6 groups, the negative control, positive control, comparison glibenklamid with a dose of 1.3 mg/kg murine mango leaf extract and test with successive doses of 2.1 mg/20 g bb murine, 4.2 mg/20 g bbmencit, and 8.4 mg/20 g bb House mouse. the parameters observed was a decrease in blood glucose levels. results in may showed that mango leaf extract with dosisi 8.4 mg/20 g bbmencit able to m, enurunkan blood glucose levels greater than the dosisi test the other 180 minutes. statistical tests using ANOVA with a 95% confidence interval (alfa = 0.05) showed the distinction meaningful decrease in blood glucose levels on the dosisi compared to the positive control. Mango leaf extract with a dose of 8.4 mg/20 g bb mice compared to glibenklamid comparison showed the absence of meaningful difference. the results of this research mengidikasikan mango leaf extract that arumanis potentially as diabete.key words: leaf mango arumanis, anti diabetic, glibenklamid, oral glucose tolerance test

Results (English) 2:

arumanis mango leaves are traditionally used by people to treat various diseases one of them is as antidiabetes.penelitian aims to determine the activity of mango leaf extract arumanis and know the most effective dose as an antidiabetic in mice. the study was conducted using oral glucose tolerance test glucose induced a dose of 3.9 g / kg bw mice mice were divided into 6 groups: negative control, positive control, comparison glibenclamide at a dose of 1.3 mg / kg bw in mice and test extract mango leaves with successive doses of 2.1 mg / 20 g bb mice, 4.2 mg / 20 g bbmencit, and 8.4 mg / 20 g bb mice. parameters measured were a decrease in blood glucose levels. the results can indicate that extracts of mango leaves with a dosage of 8.4 mg / 20 g bbmencit able m, enurunkan blood glucose levels greater than dosisi another test at minute 180. The statistical test using ANOVA with 95% confidence interval (alfa = 0.05) showed a significant difference in reduction in blood glucose levels in these dosage compared to the positive control. mango leaf extract at a dose of 8.4 mg / 20 g bb mice compared to the benchmark glibenclamide showed no significant difference. the results of this study indicate that arumanis mango leaf extract has potential as an anti diabete.
keyword: mango leaves arumanis, antidiabetic, glibenclamide, oral glucose tolerance test