Dari studi literatur tidak hanya se

Dari studi literatur tidak hanya senyawa terpenoid yang memiliki dua cincin lakton, beberapa senyawa yang memiliki satu cincin lakton ditemukan juga pada genus Mikania dibeberapa spesies yang berbeda seperti 1(10) E(3S,4R,5R,7S,8S)-14-Acetyloxy-3,4-epoxy-5-hydroxy-15senecioyloxygermacra-1(10),11(13)-dien-8,12- olide (25),1(10)E-(3S,4R,5R,7S,8S)-14-Acetyloxy-3,4-epoxy-5-hydroxy-15isovaleroyloxygermacra-1(10), 11(13)-dien-8,12-olide (26) diisolasi dari campuran bunga dan daun M. thapsoides (Catalan et al., 2003). Dari spesies M. gruziefae Bohlmann et al (1982), berhasil mengisolasi dua sesquiterpene lactones yaitu 2α-acetoxyeupatolide (27) and 2α-acetoxylaurenobiolide (28). Senyawa dengan tipe yang berbeda yaitu tipe heliangolides dan melampolides ditemukan pada bagian campuran bunga dan daun M. minima diantaranya (6S,7R,8S)-8,14,15-Triacetoxyhelianga-1(10),4,11(13)-trien-6,12-olide (29). (6S,7R,8S)-8,14-Diacetoxy-l5-hydroxyhelianga-1(10),4,-11(13)-trien-6,12-olide (30). (6S,7R,8S)-8,14-Diacetoxyhelianga-1(10),4,11(13)-trien-15-al-6,12-olide (31).(6S,7R,8S)- 8,15-Diacetoxymelampa-1(10),4,11(13)-trien-14-al-6,12-olide (32), (6S,7R,8S)-8,15-Diacetoxy-14-hydroxymelampa-1(10),4,-11(13)-triene-6,12-olide (33) (Cuenca et al., 1993).

Results (English) 1:

From the study of literature not only compounds these Terpenoids which has two ring lactones, some compounds that have a single ring lactones found also in the genus Mikania in several different species such as 1 (10) E (3S, 4R, 5R, 7S, 8S)-14-Acetyloxy-3,4-epoxy-5-hydroxy-15senecioyloxygermacra-1 (10), 11 (13)-dien-8,12-olide (25), 1 (10) E-(3S, 4R, 5R, 7S, 8S)-14-Acetyloxy-3,4-epoxy-5-hydroxy-15isovaleroyloxygermacra-1 (10)(13), 11-dien-8,12-olide (26) isolated from a mixture of flowers and leaves of m. thapsoides (Catalan et al., 2003). Of the species m. gruziefae Bohlmann et al (1982), managed to isolate the two sesquiterpene lactones: α-acetoxyeupatolide 2 (27) and α-acetoxylaurenobiolide 2 (28). Compounds with different type i.e. type heliangolides and melampolides found in the mix of flowers and leaves of m. minima are (6S, 7R, 8S) -8,14, 15-Triacetoxyhelianga-1 (10) 4, 11 (13)-trien-6.12-olide (29). (6S, 7R, 8S) -8,14-Diacetoxy-l5-hydroxyhelianga-1 (10), 4-11 (13)-trien-6.12-olide (30). (6S, 7R, 8S) -8,14-Diacetoxyhelianga-1 (10) 4, 11 (13)-trien-15-6.12-olide al (31).(6S, 7R, 8S)-8, 15-Diacetoxymelampa-1 (10) 4, 11 (13)-trien-14-6.12-olide al (32), (6S, 7R, 8S) -8,15-Diacetoxy-14-hydroxymelampa-1 (10), 4-11 (13) triene-6.12-olide (33)-(Cuenca et al., 1993).