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Toxic effect of bilirubin is neurotoksik and cell damage in General. Bilirubin can get into brain tissue. Bilirubin encephalopathy is there clinical signs caused by deposits of bilirubin in brain cells. These abnormalities can occur in acute or chronic forms. The acute form is made up of three stages; Phase 1 (the first 1-2 days): suction weak reflexes, hipotonia, convulsions; stage 2 (mid week one): the cry of shrill, hipertonia, epistotonus; stage 3 (after the first week): hipertoni. Chronic forms: in the first year: hipotoni motor, too late. After the first year are found among the movement disorders, hearing loss multi-sensorial.
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