INTRODUCTION Pall: chhers syndrome

INTRODUCTION Pall: chhers syndrome (PJS)is In inheriledamnwmnl dominant dlscasc determined by I mutation IOCIIIZDd at 19913 3 PJS results in polyps and mucocumneeous pigmentation cVIdenl smoe childhood or early adulthood ‘3 1n the Umlcd Stain P1 S m: rare dlm With an inCquwe me ofbelween one case per 60.000 people and one use per people PJS has a prevalcnw of 1 in 120,000 ve I) ve ofraoc or gender The mutant gene STKII wn LKBlhslocalndnlwplSS S’I‘Kll Is a , ga-mhne mumuon gene which is p to ‘Kr of paucnls wuh P15 and as 1‘: sh w oomplcle or pmnlmdlcation as ed ans ofSl‘Kll Diagnosis of P18 is based on clinical findings and the h'Nopauuologica] panems of polyps Hlslologically, these lesions show incmsed basilamehmin without a rise in the nnmberofmelanocyla§ThenmnifestAhon of ms [my Em be enwlmlered by adenh'st during routine exminauon in the form ofpigmenled spots in the oral cavity Round, OVII urinegldar. l 5 Imndlnmewrpalches ofbmwn oralnwst black pigmentation. inegulnrly distributed thwughom the oral mucosa, gums. hard palate and lips an: observed. The pigmented {add maculae, paniwhxly encountered around the nose and mouth. ale smaller."Mehnouc mules may be present in other body parts including me extmnities. lectum, intranasal mucosa and oonjuncdva‘Thc inlensity of manila: pigmmt is unaffected by exposure to sunlight. Padang or duappexnncc ol' the spot: is usually observed in older nae.”

Results (English) 1:

INTRODUCTION

Pall: chhers syndrome (PJS) is inclusive inheriledamnwmnl dominant dlscasc determined by the first mutation IOCIIIZDd at 19913 3 PJS results in polyps and mucocumneeous pigmentation cVIdenl SMOE childhood or early adulthood '3 1n the Umlcd Stain P1 S m: rare dlm With an inCquwe me ofbelween one case per 60,000 people and one use per people PJS has a prevalcnw of 1 in 120,000

ve I) ve ofraoc or gender The mutant gene STKII S'I'Kll is a LKBlhslocalndnlwplSS wn, ga-mhne mumuon roomates gene is p to ' Kr of paucnls wuh P15 and as 1 ': sh w oomplcle or pmnlmdlcation

as

ed ans ofSl'Kll

Diagnosis of P18 is based on clinical findings and the h'Nopauuologica] panems of polyps Hlslologically, Reviews These lesions show incmsed basilamehmin without a rise in the nnmberofmelanocyla§ThenmnifestAhon of ms [my Em Be enwlmlered by adenh'st during routine exminauon in the form ofpigmenled spots in the oral cavity Round, OVII urinegldar. l 5 Imndlnmewrpalches ofbmwn oralnwst black pigmentation. inegulnrly distributed thwughom the oral mucosa, gums. hard palate and lips late: observed. The pigmented {add maculae, paniwhxly encountered around the nose and mouth. ale smaller. "Mehnouc mules may be present in other body parts extmnities Including me. lectum, intranasal mucosa and oonjuncdva'Thc inlensity of manila: pigmmt is unaffected by exposure to sunlight. Padang or duappexnncc ol 'spot: is usually observed in older nae. "

Results (English) 2:

INTRODUCTION

Pall: Chhers syndrome (PJS) is In inheriledamnwmnl dominant DLSCASC determined by I mutation Iociiizdd at 19913 3 PJs results In polyps and mucotumneeous pigmentation cvidenl Indonesia childhood or early adulthood ' 3 1n the UMLCD Stain P1 S m: Rare DLM With an Incquwe Me Ofbelween one case per 60,000 people and one use per people PJS has a PREVALCNW of 1 in 120.000

ve I) ve Ofraoc or gender The mutant gene Stkii WN lkblhslocalndnlwplss s'i ' Kll Is A, GA-Mhne mumuon gene which Is p to ' Kr of Paucnls wuh Tianhe Airport P15 and as 1 ': sh w oomplcle or pmnlmdlcation

U.s

Ed ans Ofsl'kll

Diagnosis of P18 is based on clinical findings and the h'Nopauuologica] panems of polyps Hlslologically, these lesions show incmsed basilamehmin without a rise in the Nnmberofmelanocyla § ThenmnifestAhon of Ms [my Em be enwlmlered by adenh'st during routine Exminauon in the form ofpigmenled spots in the oral cavity Round, OVII Urinegldar. L 5 imndlnmewpalches ofbmwn Oralnwst black pigmentation. Inegulnrly distributed Thwughom the oral mucosa, gums. Hard palate and lips an: observed. The pigmented {add maculae, paniwhxly barryrubbish around the nose and mouth. Ale smaller. "Mehnouc mules may be present in other body parts including me extmnities. Lectum, intranasal mucosa and Oonjuncdva'thc inlensity of Manila: PIGMMT is unaffected by Exposure to sunlight. Padang or DUAPPEXNNCC ol ' The spot: is usually observed in older nae. "