Artocarpus merupakan salah satu gen

Artocarpus merupakan salah satu genus terpenting dalam famili moraceae. Artocarpus memiliki banyak kegunaan antara lain pengobatan sirosis, hipertensi, diabetes, peradangan, demam malaria, antiplatelet, antibakteri, antifungi, dan sitotoksik. Karya tulis ini dibuat untuk mengkaji tinjauan pustaka, kandungan senyawa dan aktivitas farmakologi dari beberapa spesies Artocarpus diantaranya Artocarpus altilis (Sukun), Artocarpus heterophyllus (Nangka), dan Artocarpus camansi (Kluwih). Genus Artocarpus memiliki kandungan senyawa yang beragam seperti terpenoid, steroid, fenolik, flavonoid, stilbenoid, arilbenzofuran, dan jacalin. Berdasarkan penelitian Artocarpus altilis memiliki aktivitas antioksidan yang lebih kuat dibandingkan dengan Artocarpus heterophyllus dengan nilai IC50 63,79 µg/mL. Sedangkan pada pengujian antidiabetes dari ketiga spesies tersebut diketahui Artocarpus altilis dan Artocarpus heterophyllus memiliki aktivitas sebagai inhibitor α-glukosidase, sedangkan Artocarpus camansi memiliki aktivitas antidiabetes yang mampu meregenerasi sel-sel β-pankreas yang rusak serta diduga dapat memperbaiki reseptor insulin. Dalam beberapa penelitian yang telah dilakukan Artocarpus altilis dan Artocarpus heterophyllus memiliki aktivitas sebagai inhibitor biosintesis melanin. Artocarpus heterophyllus memiliki daya inhibisi tirosinase yang lebih kuat dibandingkan Artocarpus atlilis terlihat dari meningkatnya persentase inhibisi yang menunjukkan bahwa pembentukan produk dopakuinon mengalami penurunan. Berdasarkan review dari beberapa jurnal penelitian, diketahui bahwa Artocarpus altilis dan Artocarpus heterophyllus memiliki aktivitas sebagai antioksidan, antidiabetes dan inhibitor biosintesis melanin. Sedangkan Artocarpus camansi memiliki aktivitas sebagai antidiabetes.

Results (English) 1:

Artocarpus is one of the most important genus in the family moraceae. Artocarpus has many uses, among others, the treatment of cirrhosis, hypertension, diabetes, inflammation, malarial fever, antiplatelet, antibacterial, antifungi, and cytotoxic. This paper examines the literature review was made for, and pharmacological activity of the compound content of several species of Artocarpus altilis including Artocarpus (Breadfruit), Artocarpus heterophyllus (Jackfruit) and Artocarpus camansi, (Kluwih). The genus Artocarpus contain compounds that are as diverse as these Terpenoids, steroids, flavonoids, phenolic stilbenoid,, arilbenzofuran, and jacalin. Artocarpus altilis research based has stronger antioxidant activity compared to Artocarpus heterophyllus 63.79 IC50 value of µ g/mL. While in testing anti diabetic third species of Artocarpus altilis is known and Artocarpus heterophyllus activity as inhibitors of α-glucosidase, Artocarpus camansi while anti diabetic activity that is able to regenerate cells of pancreatic β-cells are broken and supposedly can improve insulin receptors. In some of the research that has been done and Artocarpus altilis Artocarpus heterophyllus activity as inhibitors of the biosynthesis of melanin. Artocarpus heterophyllus have stronger tyrosinase inhibition compared Artocarpus atlilis seen from the increasing percentage of inhibition which suggests that the formation of the dopakuinon products has decreased. Based on a review of some research journals, Artocarpus altilis is known that and Artocarpus heterophyllus activity as antioxidant, melanin biosynthesis inhibitors and anti diabetic. Artocarpus camansi while activity as anti diabetic.

Results (English) 2:

Artocarpus is one of the most important genus in the family Moraceae. Artocarpus has many uses include the treatment of cirrhosis, hypertension, diabetes, inflammation, fever, malaria, antiplatelet agents, antibacterial, antifungal, and cytotoxic. This work has been made to study the literature review, compound and pharmacological activity of some species such Artocarpus Artocarpus altilis (breadfruit), Artocarpus heterophyllus (Nangka) and Artocarpus camansi (artocarpus camansi). Genus Artocarpus contains diverse compounds such as terpenoids, steroids, phenolics, flavonoids, stilbenoid, arilbenzofuran, and jacalin. Based on research Artocarpus altilis have more powerful antioxidant activity compared with Artocarpus heterophyllus with IC50 value of 63.79 mg / mL. While the antidiabetic testing of all three species are known Artocarpus Artocarpus heterophyllus altilis and has activity as an inhibitor of α-glucosidase, while Artocarpus camansi have antidiabetic activity that is able to regenerate β-cells of the pancreas are damaged and could be expected to improve insulin receptor. In some studies that have been conducted and Artocarpus heterophyllus Artocarpus altilis have activity as an inhibitor of the biosynthesis of melanin. Artocarpus heterophyllus has tyrosinase inhibition power is stronger than Artocarpus atlilis evident from the increasing percentage inhibition indicates that the product formation dopakuinon decreased. Based on a review of several research journals, note that altilis and Artocarpus Artocarpus heterophyllus have antioxidant activity, antidiabetic and melanin biosynthesis inhibitor. While Artocarpus camansi have activity as an antidiabetic.